Improved Urea Reduction Ratio and KT/V in Large Hemodialysis Patients using Two Dialyzers in Parallel

Kathleen M. Powers N.P., Michael J. Wilkowski M.D., Allen W. Helmandollar, Karl G. Koenig M.D., W. Kline Bolton M.D. Division of Nephrology, University of Virginia Health Sciences Center, Charlottesville, Virginia, 22908 USA Kathleen M. Powers, R.N., N.P. Nephrology Nurse Practitioner Division of Nephrology, Box 133 University of Virginia Health Sciences Center Charlottesville, VA 22908 Karl […]


Visit this article presented by the National Kidney and Urologic Disease Information Clearinghouse for more information on how URR and Kt/V are used to assess dialysis adequacy in general use.  Click Here   To view a comparison of dual dialyzers used in parallel and series to improve urea clearance in large hemodialysis patients. Study completed […]

A comparison of dual dialyzers in parallel and series to improve urea clearance in large hemodialysis patients

Abstract Background: Dialysis adequacy targets frequently are difficult to achieve in large hemodialysis patients. Dual dialyzers can be used to improve clearance. It is unknown whether series or parallel configurations are superior. Methods: Eighteen large hemodialysis patients (mean weight, 92.4 kg) were enrolled in a randomized, crossover trial to directly compare dual dialyzers in parallel and […]

Improving URRs in the Dialysis Unit

Tri-Counties Dialysis Center in Decatur, Ind., is a freestanding, for-profit hemodialysis facility operated by Everest Healthcare Services. The facility opened in the spring of 1996. The patient population consists primarily of elderly patients who live in the surrounding countryside and small towns of northeastern Indiana. The facility population has been steadily increasing; at the present […]

FDA Releases Final Guidance on the Reprocessing and Reuse of Single-Use Devices

On August 14, 2000, the U.S. Food and Drug Administration released its final guidance on the practice of reusing medical devices that are intended to be used only once. In the guidance, titled “Enforcement Priorities for Single-Use Devices Reprocessed by Third Parties and Hospitals” (, FDA states that it will regulate hospitals and third-party reprocessors […]

Improving Adequacy of Dialysis: Using In-Series Dialyzers

Joan Camarro Simard, Department Editor Case Study from the December 1999 issue of the ANNA Journal Hazel A. Dennison Patient Profile W.T., a 43-year-old male, began on hemodialysis in 1996 for membranoproliferative glomerulonephritis (MPGN). His height was 5’10” and his weight was 330 lbs. He supported his wife and 3 children by working as a […]

External Visual Indicator for Transducer Protectors

Philip Andrysiak, BS, MBA, CHT Recent incidents of blood contamination of the internal pressure monitoring lines have raised concerns with respect to cross-contamination and patient safety. The MPC-75 moves the redundant transducer protector from the inside of the machine to the outside where it can be visually inspected for primary transducer protector failure. Cross-contamination with […]

Hemofiltration and double high flux dialysis: risks and benefits

Abstract Convective therapies such as hemofiltration, hemodiafiltration and double high flux dialysis have been shown to improve treatment delivered and treatment tolerance when compared to conventional dialysis therapies. The risk associated with these treatments is primarily in the quality of the substitution fluid. Technological advances now permit online-produced substitution fluid, thereby significantly reducing the cost associated […]

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